贺海燕，研究员，博士生导师，副所长。2007年本科毕业于天津大学。2012年于中国科学院上海有机化学研究所获生命有机化学博士学位。获国家海外引进高层次人才青年项目、国家自然科学基金-面上等项目资助。 院校引进人才，2021年加入院校，曾在加拿大英属哥伦比亚大学任职博士后/助理研究员。

长期从事降糖降脂及抗肿瘤药物的发现及结构优化，绿色生物合成等领域的研究。发现并揭示了多个药用活性天然产物的生物合成途径，阐明了十余个具有新颖功能酶的催化机制，可应用于天然产物和临床药物的结构修饰及改造。主持或参于国家和省部级科研课题6项，在Chem Soc Rev, Nat Chem, JACS，Angew Chem等领域内著名学术期刊发表论文十余篇，他因700余次。

1. Yun Wang#, Jiangtao Zhang, Ran Shi, Siyuan Zhou, Shigui Chen, Ruofei Li*, Wei Huang*, Hai-Yan He*, Nitramine Formation via a Cryptic Non-Ribosomal Peptide Synthetase-Dependent Strategy in N-Nitroglycine Biosynthesis. Angew. Chem. Int. Ed. 2025, e202507866. (IF=16.1)

2. Songya Zhang#, Shuai Fan#, Haocheng He#, Jing Zhu, Lauren Murray, Gong Liang, Shi Ran, Yi Zhun Zhu, Max J Cryle*, Hai-Yan He*, Youming Zhang*. Cyclic natural product oligomers: diversity and (bio)synthesis of macrocycles. Chem. Soc. Rev. 2025, 54, 396-464. (IF=40.4)

3. Hai-Yan He*, Haruka Niikura, Yi-Ling Du, Katherine S. Ryan*. Synthetic and biosynthetic routes to nitrogen-nitrogen bonds. Chem. Soc. Rev. 2022, 51, 2991-3046. (IF=60.6)

4. Hai-Yan He#, and Katherine S. Ryan*. Glycine-derived Nitronates Bifurcate Between O-Methylation and Denitrification in Bacteria. Nat. Chem. 2021, 13, 599-606. (IF=19.2)

5. Hai-Yan He#, Alyssa C. Henderson, Yi-Ling Du, and Katherine S. Ryan*. Two-Enzyme Pathway Links L-Arginine to Nitric Oxide in N-Nitroso Biosynthesis. J. Am. Chem. Soc. 2019, 141, 4026–4033. (IF=14.6)

6. Hai-Yan He#, Man-Cheng Tang, Feng Zhang, and Gong-Li Tang*. Cis-Double Bond Formation by Thioesterase and Transfer by Ketosynthase in FR901464 Biosynthesis. J. Am. Chem. Soc. 2014, 136, 4488–4491. (IF=12.1)

7. Hai-Yan He#, Hua Yuan, Man-Cheng Tang, and Gong-Li Tang*. An Unusual Dehydratase Acting on Glycerate and a Ketoreductase Stereoselectively Reducing a-Ketone in Polyketide Starter Unit Biosynthesis. Angew. Chem. Int. Ed. 2014, 53, 11315 –11319. (IF=13.7)