张赟，1986年出生，中国医学科学院肿瘤医院研究员，博士生导师。2004年考入北京大学生命科学学院，2008年获得学士学位。之后在美国杜克大学王小凡教授指导下获博士学位。获国家海外高层次人才计划青年项目支持。
      院校引进人才，2023年加入院校。在美国麻省理工学院怀特海德研究所Robert A. Weinberg教授实验室进行博士后研究，主要从事肿瘤微环境和肿瘤转移分子机制的研究。

主要研究肿瘤异质性形成和肿瘤微环境影响转移过程的分子机制，以及分子肿瘤学基础研究和细胞治疗相关的新技术研发。

1．Lambert, A.W.^#, Zhang, Y.^#, Weinberg, R.A. (2024) Cell-intrinsic and microenvironmental determinants of metastatic colonization. Nat. Cell Biol. 26, 687–697. (IF = 28.213)

2．Li, L., Zhu, R., Zhou, H., Cui, C.‐P., Yu X., Liu, Y., Yin, Y., Li, Y., Feng, R., Katz, J. P., Zhao, Y. Zhang, Y.*, Zhang, L.*, Liu, Z.* (2023) All‐Trans Retinoic Acid Promotes a Tumor Suppressive OTUD6B‐β‐TrCP‐SNAIL Axis in Esophageal Squamous Cell Carcinoma and Enhances Immunotherapy. Adv. Sci. 10(16):e2207458. (IF = 17.521)

3．Zhang, Y.*, Donaher, J. L., Das, S., Li, X., Reinhardt, F., Krall, J. A., Lambert, A., Thiru, P., Keys, H. R., Khan, M., Hofree., M., Wilson, M. M., Yedier-Bayra, O., Lack, N.A., Onder, T. T., Bagci-Onder, T., Tyler, M., Tirosh, I., Regev, A., Lees, J., Weinberg, R.A.* (2022) Genome-wide CRISPR screen identifies PRC2 and KMT2D-COMPASS as regulators of distinct EMT trajectories that contribute differentially to metastasis. Nat. Cell Biol. 24(4):554-564. (IF = 28.213, C100)

4．Zhang, Y.*, Wang, X. -F.* (2022) 肿瘤微环境调控癌症发生发展的研究概述. Microenvironmental regulation of tumor initiation and development (in Chinese). SCIENTIA SINICA Vitae (中国科学: 生命科学), 52: 1377-1390. (IF = 1.237)

5．Wang, E., Xiang, K., Zhang, Y.*, Wang, X. -F.* (2022) Patient-derived organoids (PDOs) and PDO-derived xenografts (PDOXs): New opportunities in establishing faithful pre-clinical cancer models, Journal of the National Cancer Center, 2, 263-276.

6．Zhang, Y.*, Weinberg, R.A.* (2018). Epithelial-to-mesenchymal transition in cancer: complexity and opportunities. Front Med., 12(4), 361-373. (IF = 9.927, C100, ESI, F1000)

7．Zhang, Y., Alexander, P., Wang, X. -F. (2017) TGF-β family signaling in the control of cell proliferation and survival. Cold Spring Harb Perspect Biol, 9(4), a022145. (IF = 9.708, C100)

8．Zhang, Y., Wang, X. -F. (2015) A niche role for cancer exosomes in metastasis. Nat. Cell Biol., 17, 709-711. (IF = 18.699, C100)

9．Zhang, Y., Yang, P., Wang, X.-F. (2014) Microenvironmental regulation of cancer metastasis by microRNAs. Trends Cell Biol., 24, 153-160. (IF = 12.007, C100)

10．Zhang, Y.#, Yang, P.#, Sun, T., Li, D., Xu, X., Rui, Y., Li, C., Chong, M., Ibrahim, T., Mercatali, L., Amadori, D., Lu, X., Xie, D., Li, Q.-J., Wang, X.-F. (2013) Mir-126 and mir-126* repress recruitment of mesenchymal stem cells and inflammatory monocytes to inhibit breast cancer metastasis. Nat. Cell Biol., 15, 284-294. (IF = 20.058, C100)